In 1997 Natali graduated from the Higher Theater School named after Shchukin. From 1997 to 2012 she has been an actress of the Moscow Drama Theater named after Gogol. Since 1997 she has acted in films, making her debut in the film At the Dawn of a Foggy Youth. She has played more than forty roles, mostly starred in dramatic roles. In 2003, the actress became known across the country thanks to the role of Pauline in the TV series Other Life, where purposeful, intelligent and sociable girl from a small provincial town comes to Moscow to start a new life.